1.
International Journal of Pediatrics
;
(6): 21-23, 2011.
Article
in Chinese
| WPRIM
| ID: wpr-381496
ABSTRACT
In rotavirus infection, NF-κB plays an important role in regulation of host defense and pathogenic of rotavirus. On the one hand, by the signal regulation mechanism of NF-κ Bmediated, host plays antiviral effect and immune-related role. On the other hand, by blocking NF-κB nuclear accumulation and other reactions, rotavirus evades the host immune response. Consequently, the outcome of rotavirus infection may depend on dominant way of NF-κ Bregulating.